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The Mouth Cancer Foundation Online Support Group Mouth Cancer Forums Members Forums Medications, Treatment, Procedures Pentoxifylline|
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| Pentoxifylline
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Quick question - has anyone else been prescribed pentoxifylline? I am doing really well - no problems at all re. scars, flap, swallowing, eating, taste etc BUT (isn't there always a but?) I have a small (maybe 1/4 cm) patch of gum on the inside edge of where my lower left wisdom tooth would be that has separated to expose the bone (X-Rays are good no underlying damage to the jaw). My oncologist has prescribed pentoxifylline to increase blood flow and so encourage the gum to grow back over. Just wondered if anyone out there had experienced this and how they where treated
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Hello Norm
You are being treated for Osteoradionecrosis of the mandible. Usually it is managed conservatively and with hyperbaric oxygen treatments. Pentoxifylline has been used for the treatment of radiation-related soft tissue injury with some success. Its utility in treatment for mandibular ORN is unknown, however. The use of this drug is described in Major healing of refractory mandible osteoradionecrosis after treatment combining pentoxifylline and tocopherol: a phase II trial. Let us know how you do. Best wishes Vinod 
This message has been edited. Last edited by: Dr Vinod K Joshi,
Disclaimer: Please see your own dentist/doctor for a proper diagnosis as my words should not, in any circumstances, be taken as dental/medical advice. "If you see what is small as it sees itself, and accept what is weak for what strength it has, and use what is dim for the light it gives, then all will go well. This is called Acting Naturally." Lao-Tsu, Tao Teh King |
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Hi Dr Vinod,
Well it works! The tiny piece of bone on the surface came away last night and the gum underneath has just about healed over. So heres hoping! Norman. |
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Hello Norm
Great news, keep well. Best wishes Vinod Disclaimer: Please see your own dentist/doctor for a proper diagnosis as my words should not, in any circumstances, be taken as dental/medical advice. "If you see what is small as it sees itself, and accept what is weak for what strength it has, and use what is dim for the light it gives, then all will go well. This is called Acting Naturally." Lao-Tsu, Tao Teh King |
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Hello Norm
I hope you are keeping well. Let us know how you are doing. Best wishes Vinod Disclaimer: Please see your own dentist/doctor for a proper diagnosis as my words should not, in any circumstances, be taken as dental/medical advice. "If you see what is small as it sees itself, and accept what is weak for what strength it has, and use what is dim for the light it gives, then all will go well. This is called Acting Naturally." Lao-Tsu, Tao Teh King |
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